StimulusBio’s Programmable Cell Interface technology (sbPCI) enables quantitative and spatial control of surface presentation, membrane integration in <4 hours and rapid iteration for testable configurations in days.
Activation reagents are fixed, cell therapies are not. Bead-based systems require magnetic removal and polymeric systems often stipulate specific buffers and cytokines. This leads to ongoing culture manipulation and iterative, costly component additions that increase development complexity and resource demands. CellPilot Expanders lower the costs and workfow burdens of standard activation reagents.
For immune cell programs, the bottleneck is not only biology. Cell line development often requires engineering that takes up to 9 months of cloning and qualification. Add on cell line maintenance and you burn through significant material and budget before you can screen for the best option. CellPilot Explorer reduces the time and cost of configuring and optimizing signal design.
When standard differentiation protocols can’t achieve the desired outcome, identifying the optimal combination of biological signals can take months of iterative testing. Challenging cell types, specialized phenotypes, and emerging therapeutic applications often require signaling approaches that are not addressed by off-the-shelf solutions. CellPilot Custom accelerates discovery and optimization of tailored signal combinations.
The CellPilot product line enables scientists to tailor signal presentation with quantitative control of cell interactions, streamlined interrogation of cell mediators, high-throughput selection of optimal formulation, & significant time & cost savings.
StimulusBio’s Programmable Cellular Interface (sbPCI) technology delivers a transformative solution for immune cell screening and functional characterization. The technology enables direct functionalization of cells by enabling rapid, modular presentation of bioactive molecules (antigens, costimulatory ligands, cytokines, etc.) on biocompatible presenting cells.
